Key result
Ruptured abdominal aortic aneurysm repair was associated with a 22.9% operative and in-hospital mortality rate, compared with 1.9% for non-ruptured aneurysms.
Why the study?
What are the clinical risk factors associated with operative and in-hospital mortality in patients undergoing surgical repair of ruptured abdominal aortic aneurysm?
Cohort (n=105)
No
What are the clinical risk factors associated with operative and in-hospital mortality in patients undergoing surgical repair of ruptured abdominal aortic aneurysm?
Absolute Event Rate: 22.9% vs 1.9%
Preoperative hemodynamic instability, severe blood loss, and postoperative bowel ischemia are significant predictors of mortality following surgical repair of ruptured AAA.
High mortality after ruptured AAA repair warrants preventive emphasis; leaves open modifiable predictors in prospective cohorts.
PURPOSE: The purpose of this study is to identify the risk factors affecting the high mortality rates associated with the treatment of ruptured abdominal aortic aneurysm (AAA). METHODS: In this retrospective study, the subjects consisted of 105 patients who underwent repair of ruptured AAA at our institution from December 1984 to March 2012. We compared the patients of ruptured AAA in survival group with those in death group to evaluate the clinical factors in ruptured AAA mortality. RESULTS: The operative and in-hospital mortality of ruptured AAA patients was 22.9% compared with 1.9% for that of non-ruptured AAA patients. The mean hemoglobin level was significantly lower in death group than in survival group. Intraoperative bleeding volume was significantly higher in death group than in survival group. Cox proportional hazard analysis showed that level 3 or 4 according to the Rutherford classification, preoperative hemoglobin level of less than 9.0 g/dl, intraoperative blood loss volume of more than 3000 ml, postoperative bowel ischemia and class 3 or 4 according to the Fitzgerald classification were significantly associated with high mortality. CONCLUSION: These findings showed that every effort to maintain preoperative hemodynamic stability reduce volumes of blood loss in operation, and to minimize postoperative deterioration of organ functions would be essential to improve patient survival.
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Kunishige et al. (2013) conducted a cohort in Ruptured abdominal aortic aneurysm (n=105). Ruptured abdominal aortic aneurysm vs. Non-ruptured abdominal aortic aneurysm was evaluated on Operative and in-hospital mortality. Ruptured abdominal aortic aneurysm repair was associated with a 22.9% operative and in-hospital mortality rate, compared with 1.9% for non-ruptured aneurysms.