Key result
Three recombinant Coxsackievirus A4 groups, including a novel C2 lineage, were identified as major causative agents of herpangina and HFMD in Yancheng, China.
Why the study?
To better understand the pathogen spectrum causing herpangina and the circulation of Coxsackievirus A4 in Yancheng, China.
Population
Stool samples from herpangina and HFMD cases in Yancheng, China
Design
Virological and genetic surveillance study
Authors
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Identification of a novel recombinant CV-A4 associated with herpangina and HFMD in China highlights the ongoing evolution and recombination of enteroviruses.
Observational
Identification of a novel recombinant CV-A4 associated with herpangina and HFMD in China highlights the ongoing evolution and recombination of enteroviruses.
Guo et al. (2020) conducted an observational in Herpangina and Hand, Foot, and Mouth Disease (HFMD). Coxsackievirus A4 was evaluated on Identification and genetic characterization of enteroviruses. Three recombinant Coxsackievirus A4 groups, including a novel C2 lineage, were identified as major causative agents of herpangina and HFMD in Yancheng, China.
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