Key result
Discarding a volume of blood equal to 6 times the catheter dead space from a heparinized arterial line provides accurate activated partial thromboplastin time values.
Why the study?
Does discarding a specific volume of blood from a heparinized arterial line provide accurate activated partial thromboplastin time compared to venous samples in adult critical care patients?
Does discarding a specific volume of blood from a heparinized arterial line provide accurate activated partial thromboplastin time compared to venous samples in adult critical care patients?
To obtain accurate aPTT values from a heparinized arterial line in non-systemically heparinized adult critical care patients, a discard volume of 6 times the catheter dead space is adequate.
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May support 6× dead-space discard for accurate aPTT from heparinized arterial lines; leaves open prospective validation.
Laxson et al. (1994) conducted a review in Adult critical care patients with heparinized arterial lines. Discarding blood from arterial lines vs. Venous blood samples was evaluated on Activated partial thromboplastin time (aPTT). Discarding a volume of blood equal to 6 times the catheter dead space from a heparinized arterial line provides accurate activated partial thromboplastin time values.
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