Key result
Among idiopathic dilated cardiomyopathy patients in sinus rhythm, those with LVEF <30% had higher rates of nonsustained VT (44% vs 22%, P<0.05) and T wave alternans (59% vs 37%, P<0.05).
Why the study?
Do noninvasive arrhythmia risk predictors predict overall mortality and arrhythmic events in patients with idiopathic dilated cardiomyopathy?
Observational (n=159)
Do noninvasive arrhythmia risk predictors predict overall mortality and arrhythmic events in patients with idiopathic dilated cardiomyopathy?
In patients with idiopathic dilated cardiomyopathy, severe left ventricular dysfunction (LVEF < 30%) is associated with a significantly higher prevalence of noninvasive arrhythmia risk markers.
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LVEF <30% was associated with higher NSVT and TWA prevalence in IDCM; leaves open whether these markers predict mortality or arrhythmic events.
Grimm et al. (1998) conducted an observational in idiopathic dilated cardiomyopathy (n=159). LVEF < 30% vs. LVEF ≥ 30% was evaluated on overall mortality and arrhythmic events (sustained VT or VF, or sudden cardiac death). Among idiopathic dilated cardiomyopathy patients in sinus rhythm, those with LVEF <30% had higher rates of nonsustained VT (44% vs 22%, P<0.05) and T wave alternans (59% vs 37%, P<0.05).
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