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October 6, 2020Netherlands Heart JournalOpen Access

Surgical treatment of transcatheter aortic valve infective endocarditis

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Key result

Surgical explantation of infected transcatheter aortic valve prostheses was associated with an overall postoperative in-hospital mortality of 28%.

Why the study?

Survival of patients with an infected TAVI prosthesis is generally poor, but only a minority (10%) have undergone surgical explantation.

Design

Systematic literature review

Authors

PMPietro Giorgio MalvindiCross-Cutting CardiologySLSuvitesh LuthraUniversity of SouthamptonSSSajiram SarvananthanSt Bartholomew's Hospital

Discussion

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Implication

Survival poor in infected TAVI despite limited explantation; leaves open optimal management strategies.

Study Design

Type

Systematic Review (n=107)

Structured PICO

P
Population
107 elderly patients (mean age 76 years, 72% male) who underwent surgical explantation of an infected transcatheter aortic valve prosthesis.
I
Intervention
Surgical explantation of infected TAVI prosthesis and surgical aortic valve replacement
O
Outcome
Postoperative in-hospital mortalityhard clinical

Surgical explantation of infected TAVI prostheses is associated with a 28% in-hospital mortality, which may represent a viable life-saving option for a highly lethal condition.

Limitations

  • Inclusion of small series and case reports
  • Long-term survival data were lacking in most case series
  • A formal meta-analysis could not be carried out
  • Lack of long-term survival data in most case series
  • Inability to perform a formal meta-analysis

Cite This Study

Malvindi et al. (2020) conducted a systematic review in Transcatheter aortic valve infective endocarditis (n=107). Surgical explantation of TAVI prosthesis was evaluated on Postoperative in-hospital mortality. Surgical explantation of infected transcatheter aortic valve prostheses was associated with an overall postoperative in-hospital mortality of 28%.

synapsesocial.com/papers/6a939b44ecce1279b469664chttps://doi.org/10.1007/s12471-020-01494-y
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Surgery for Fulminant Prosthetic Valve Endocarditis after Transapical Transcatheter Aortic Valve-in-Valve Implantation2013 · 12 citations
  2. 2Prosthetic valve endocarditis 7 months after transcatheter aortic valve implantation diagnosed with 3D TEE2016 · 11 citations
  3. 3Pseudomonas aeruginosa Infective Endocarditis Following Transcatheter Aortic Valve Implantation: A Note of Caution2016 · 13 citations
  4. 4Infective endocarditis after transcatheter aortic valve implantation with LOTUS valve2016 · 8 citations
  5. 5Infective endocarditis 4 months after transapical aortic valve implantation with Edwards SAPIEN™ XT2013 · 6 citations