Key result
Enterovirus receptors are located mainly in the microsomal fraction of primate cells, and their virus-adsorbing function depends on the integrity of a protein portion of the membrane lipoproteins.
Population
Primate cells susceptible to enteroviruses
Comparison
Cell disruption and treatment with proteolytic… vs Intact cells and untreated cell fractions
Design
Preclinical
Authors
Loading...
Should not yet alter clinical management of enteroviral disease; leaves open receptor-targeted strategies in primate models.
This basic science study demonstrates that enterovirus receptors are integral to cellular membrane lipoproteins and depend on protein integrity for virus adsorption.
Holland et al. (1961) studied Enterovirus susceptibility. Enterovirus receptors are located mainly in the microsomal fraction of primate cells, and their virus-adsorbing function depends on the integrity of a protein portion of the membrane lipoproteins.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: