Population
Polarized monkey kidney (Vero C1008) and human intestinal (Caco-2) epithelial cells
Design
Preclinical
Authors
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Supports dual-surface entry models; leaves open human gut pathogenesis relevance.
Poliovirus can efficiently infect polarized epithelial cells from both apical and basolateral surfaces, which has implications for viral pathogenesis in the human gut.
Tucker et al. (1993) studied this question.
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