Population
Two polarized epithelial cell lines: Vero C1008 and Caco-2 infected with poliovirus
Design
Preclinical
Authors
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Directional release from intestinal epithelia may influence poliovirus dissemination; leaves open confirmation in animal models and clinical relevance.
Poliovirus is released vectorially from the apical surface of human intestinal epithelial cells, which has significant implications for viral pathogenesis in the human gut.
Tucker et al. (1993) studied this question.
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