Key result
Bioprostheses were associated with a higher actuarial risk of prosthetic valve endocarditis than mechanical valves (0.65%/yr vs 0.42%/yr) but a lower risk of death (0.12%/yr vs 0.19%/yr).
Why the study?
Does the type of prosthetic valve (bioprosthetic vs mechanical) affect the risk of prosthetic valve endocarditis and subsequent mortality?
Population
1,810 patients who underwent valve replacement between 1971 and 1981
Comparison
Bioprosthetic valves (n=605) vs Mechanical valves (n=1205)
Design
Cohort
Follow-up
average 5.0 years
Authors
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May inform valve selection discussions; leaves open whether randomized trials will confirm these associations.
Cohort (n=1,810)
Does the type of prosthetic valve (bioprosthetic vs mechanical) affect the risk of prosthetic valve endocarditis and subsequent mortality?
Absolute Event Rate: 0.65% vs 0.42%
Bioprosthetic valves are associated with a higher risk of prosthetic valve endocarditis but a lower risk of death compared to mechanical valves, with medical therapy showing higher success rates in bioprostheses.
M Turina (1982) conducted a cohort in Prosthetic valve endocarditis (n=1,810). Bioprostheses vs. Mechanical valves was evaluated on Actuarial risk of prosthetic valve endocarditis. Bioprostheses were associated with a higher actuarial risk of prosthetic valve endocarditis than mechanical valves (0.65%/yr vs 0.42%/yr) but a lower risk of death (0.12%/yr vs 0.19%/yr).
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