Key result
High abdominal perimeter was associated with significantly worse left ventricular diastolic function, including decreased septal e' velocity and increased E/e' ratio and left atrial volume.
Why the study?
Diastolic dysfunction plays a leading role in heart failure and may increase with abdominal perimeter, but its influence on echocardiographic parameters required better understanding.
Does high abdominal perimeter worsen echocardiographic parameters of diastolic function in outpatients?
Cross-Sectional (n=82)
No
Does high abdominal perimeter worsen echocardiographic parameters of diastolic function in outpatients?
Increased abdominal perimeter is significantly associated with echocardiographic markers of left ventricular diastolic dysfunction and adverse structural remodeling.
Answers are grounded in this paper and cite their sources.
Should not change practice; hypothesis-generating link between abdominal obesity and diastolic dysfunction requires prospective validation.
Heart failure is one of the biggest causes of morbidity and mortality globally and left ventricular diastolic dysfunction plays a leading role in this clinical context. Diastolic dysfunction may increase in predisposition with an increase in abdominal perimeter. The objective of this work was to understand better the influence of abdominal perimeter on echocardiographic parameters of diastolic function. Abdominal perimeter was measured and a transthoracic echocardiogram was performed on all individuals who sought outpatient consultation at a local health unit in the central region of mainland Portugal. These individuals were separated into two groups according to the abdominal perimeter cutoff values recommended by the World Health Organization. The two abdominal perimeter groups were related to the echocardiographic parameters of diastolic dysfunction and other relevant parameters: Ejection fraction, left atrial volume, E/A ratio, E wave velocity, E/e' ratio, lateral e', septal e', tricuspid regurgitant jet velocity, E wave deceleration time, diameter and mass of the left ventricle. The sample was presented by 82 individuals of Caucasian race, of which 44 individuals (53.7%) belonged to the normal abdominal perimeter group and 38 individuals (46.3%) to the high abdominal perimeter group. In individuals with greater abdominal circumference, there was a statistically significant decrease in septal e' (p<0.0001), lateral e' (p=0.004) and LVEF (p=0.046) and also a significant increase in the E/ ratio. e' (p=0.008), left atrial volume (p<0.0001), left ventricular mass (p=0.004), tricuspid regurgitant jet velocity (p= 0.007) and left ventricular diameter (p=0.022 ) ). Measuring abdominal perimeter can alert to possible changes in diastole, with transthoracic echocardiography being the gold standard test in this context.
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Duarte et al. (2025) conducted a cross-sectional in Left ventricular diastolic dysfunction (n=82). High abdominal perimeter vs. Normal abdominal perimeter was evaluated on Septal e' velocity (cm/s) (p=<0.0001). High abdominal perimeter was associated with significantly worse left ventricular diastolic function, including decreased septal e' velocity and increased E/e' ratio and left atrial volume.
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