The symptoms related to sickle cell crises were known by various names in Africa, long before they were recognized in the western hemisphere1. Symptoms of sickle cell anemia could be tracked back to year 1670 in one Ghanian family2. It was in 1910 when James Herrick3 observed, “peculiar elongated sickle shaped RBCs” in the blood of an anemic black medical student, and then the scientific community came to know about it.
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