Key result
Corticosteroid use in children undergoing congenital heart surgery was not associated with a difference in mortality (OR 1.13; 95% CI 0.98-1.30) but was linked to increased morbidity.
Why the study?
Do corticosteroids improve outcomes in children undergoing congenital heart surgery?
Population
46,730 children (0 to 18 years of age) undergoing congenital heart surgery
Comparison
Corticosteroids vs No corticosteroids
Design
Cohort
Follow-up
in-hospital
Authors
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Cautions against routine corticosteroid use in pediatric congenital heart surgery; leaves open need for RCTs on morbidity.
Observational (n=46,730)
Yes
Do corticosteroids improve outcomes in children undergoing congenital heart surgery?
Odds Ratio: 1.13 (95% CI 0.98–1.3)
In children undergoing congenital heart surgery, corticosteroid use was not associated with a mortality benefit but was linked to increased morbidity, including longer hospital stays and higher infection rates.
Pasquali et al. (2010) conducted an observational in Congenital heart surgery (n=46,730). Corticosteroids vs. Nonrecipients was evaluated on In-hospital mortality (OR 1.13, 95% CI 0.98 to 1.30). Corticosteroid use in children undergoing congenital heart surgery was not associated with a difference in mortality (OR 1.13; 95% CI 0.98-1.30) but was linked to increased morbidity.
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