Key result
Elective CABG induced postoperative IL-6 release in all patients, peaking at 8 hours, with a weak correlation to total operation time (r=0.69, p<0.05), while TNF was not detected.
Why the study?
Does elective cardiopulmonary bypass induce the release of TNF-alpha and IL-6 in patients undergoing CABG?
Observational (n=13)
Does elective cardiopulmonary bypass induce the release of TNF-alpha and IL-6 in patients undergoing CABG?
Elective cardiopulmonary bypass triggers a significant postoperative release of IL-6, but not TNF-alpha, which weakly correlates with total operation time.
Authors
No takes yet. Share an insight, caveat, or question.
IL-6 but not TNF rises after elective CABG; leaves open its prognostic value or role for targeted anti-inflammatory strategies.
Almdahl et al. (1993) conducted an observational in Elective coronary artery bypass grafting (n=13). Elective coronary artery bypass grafting (CABG) was evaluated on Release of tumour necrosis factor-α (TNF) and interleukin 6 (IL-6). Elective CABG induced postoperative IL-6 release in all patients, peaking at 8 hours, with a weak correlation to total operation time (r=0.69, p<0.05), while TNF was not detected.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: