Key result
The after-hyperpolarization following depolarization of rabbit superior cervical ganglion cells by acetylcholine is due to the activity of an electrogenic sodium pump, which is prevented by ouabain.
The after-hyperpolarization following acetylcholine depolarization in rabbit superior cervical ganglion cells is mediated by an electrogenic sodium pump, which is mechanistically distinct from the positive after-potential and P wave.
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No immediate clinical implications from rabbit ganglia; leaves open human autonomic validation.
Lees et al. (1974) studied this question. Acetylcholine and Ouabain was evaluated on Amplitude and rate of development of after-hyperpolarization. The after-hyperpolarization following depolarization of rabbit superior cervical ganglion cells by acetylcholine is due to the activity of an electrogenic sodium pump, which is prevented by ouabain.
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