Key result
The anaerobic threshold, measured during cardiopulmonary stress testing, is a valuable diagnostic and prognostic marker for evaluating patients with dyspnea and cardiopulmonary diseases.
Measurement of the anaerobic threshold during cardiopulmonary exercise testing is a valuable tool for diagnosing the etiology of dyspnea and determining prognosis in patients with heart failure and those undergoing noncardiac surgery.
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Supports anaerobic threshold assessment in dyspnea evaluation; leaves open need for prospective trials to refine thresholds and guideline integration.
The anaerobic threshold (AT) is defined as the oxygen consumption level above which energy production becomes determined by anaerobic metabolism, which causes a sustained increase in lactate and metabolic acidosis. The AT, as measured by cardiopulmonary stress testing, is ubiquitously used to determine the prognosis and diagnosis of cardiovascular and respiratory diseases. This measurement can help clinicians in the functional evaluation of patients and as guidance for rehabilitation and therapy. This article reviews the pathophysiological aspects and methods of measurement of the AT during a cardiopulmonary stress test, and its clinical use in assessing cardiac and respiratory diseases.
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Madonna et al. (2012) conducted a review in Dyspnea, Cardiovascular and Respiratory Diseases. Anaerobic Threshold (AT) measurement was evaluated. The anaerobic threshold, measured during cardiopulmonary stress testing, is a valuable diagnostic and prognostic marker for evaluating patients with dyspnea and cardiopulmonary diseases.
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