Why the study?
Does type 1 diabetes mellitus of short duration alter cardiac mass, function, carotid intima-media thickness, or lipid levels in children and adolescents compared to healthy controls?
Population
20 children and adolescents with type 1 diabetes mellitus of short duration, mean age 11.9 +/- 3.6 years…
Comparison
Type 1 diabetes mellitus vs 20 healthy non-diabetic controls, aged 12.1 +/…
Design
Case-control
Authors
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Supports early lipid monitoring in pediatric T1DM; leaves open whether dyslipidemia predicts later cardiac or vascular changes.
Does type 1 diabetes mellitus of short duration alter cardiac mass, function, carotid intima-media thickness, or lipid levels in children and adolescents compared to healthy controls?
Children and adolescents with short-duration type 1 diabetes exhibit early dyslipidemia (elevated LDL and Lp(a)) before the onset of detectable structural or functional cardiac and vascular changes.
Günczler et al. (2002) studied this question.
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