Key result
Worsening preoperative left ventricular ejection fraction (LVEF <30%) was associated with significantly reduced unadjusted 5-year survival compared to LVEF 40-49% (58% vs 81.2%) in patients undergoing isolated mitral valve repair.
Why the study?
Clinical outcomes after isolated mitral valve repair in patients with reduced LVEF (<50%), focusing on perioperative characteristics, survival, and freedom from reoperations, required analysis.
Cohort (n=557)
No
Absolute Event Rate: 58% vs 81.2%
p-value: p=<0.001
Isolated mitral valve repair can be performed safely in patients with reduced LVEF, though worsening preoperative LVEF correlates with increased perioperative mortality and reduced long-term survival.
No takes yet. Share an insight, caveat, or question.
MV repair may be feasible in reduced LVEF; leaves open optimal selection versus alternatives in prospective trials.
Noack et al. (2019) conducted a cohort in Symptomatic mitral regurgitation with reduced left ventricular ejection fraction (n=557). LVEF <30% vs. LVEF 40-49% was evaluated on 5-year survival (p=<0.001). Worsening preoperative left ventricular ejection fraction (LVEF <30%) was associated with significantly reduced unadjusted 5-year survival compared to LVEF 40-49% (58% vs 81.2%) in patients undergoing isolated mitral valve repair.
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