Key result
The cold pressor test elicited a significantly higher systolic blood pressure increase in pregnant women who later developed pre-eclampsia compared to those who remained healthy (14.2 vs 8.5 mmHg; P=0.02).
Why the study?
Does the blood pressure response to a cold pressor test predict the development of pre-eclampsia in pregnant women?
Population
123 pregnant women between the 16th to 20th week of gestation
Comparison
Cold pressor test vs Women who did not develop pre-eclampsia
Design
Cohort
Follow-up
until delivery
Authors
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May support cold pressor response as early pre-eclampsia marker; leaves open prospective validation before clinical adoption.
Cohort (n=123)
No
Does the blood pressure response to a cold pressor test predict the development of pre-eclampsia in pregnant women?
Absolute Event Rate: 14.2% vs 8.5%
p-value: p=0.02
An increased blood pressure response to the cold pressor test between 16-20 weeks of gestation may serve as an early marker for the subsequent development of pre-eclampsia.
Woisetschläger et al. (2000) conducted a cohort in Pre-eclampsia (n=123). Cold pressor test vs. Healthy pregnant women was evaluated on Increase in systolic blood pressure during the cold pressor test (mmHg) (p=0.02). The cold pressor test elicited a significantly higher systolic blood pressure increase in pregnant women who later developed pre-eclampsia compared to those who remained healthy (14.2 vs 8.5 mmHg; P=0.02).
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