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A non‐leukemogenic strain of Friend leukemia virus (FLV) propagated in vitro interfered with infection by murine sarcoma virus (Moloney) (MSV) and acted as a helper of defective MSV. This suggests that the non‐leukemogenic strain of FLV is infectious. After prolonged propagation in vitro, the leukemogenicity of a highly leukemogenic strain of FLV gradually decreased, while the infectivity assayed by interference with MSV infection remained unchanged.
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Yoshikura et al. (1969) studied this question.
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