Key result
Subjects receiving 81 mg aspirin daily could undergo dental extraction without bleeding risks, with similar bleeding outcomes across all groups at 48 hours and 5 days post-operatively.
Why the study?
Does aspirin 81 mg daily increase bleeding after dental extraction in subjects undergoing simple or surgical extraction?
Cohort (n=189)
Does aspirin 81 mg daily increase bleeding after dental extraction in subjects undergoing simple or surgical extraction?
Patients taking 81 mg aspirin daily can safely undergo dental extraction without significant long-term bleeding risks.
Supports continuing low-dose aspirin for dental extraction; leaves open confirmation in randomized trials.
UNLABELLED: Acetylsalicylic acid (ASA) generically known as aspirin is used clinically as an analgesic, antipyretic, anti-inflammatory and as a medication to prevent platelet aggregation. Many studies have investigated bleeding associated with ASA. OBJECTIVE: The aim of this study was to determine if ASA was associated with bleeding after dental extraction. PATIENTS AND METHODS: One hundred and eighty-nine subjects were divided into four groups. Group 1A subjects who received ASA, underwent simple extraction. Group 1B subjects who received ASA, underwent surgical extraction. Group 2A subjects who did not receive ASA, underwent simple extraction which served as control group. Group 2B subjects who did not receive ASA, underwent surgical extraction which also served as control group. RESULTS: The results showed that Group 1B was the only group which showed bleeding after 24 h. All groups had similar results after 48 h and 5 days post-operatively. CONCLUSION: The study concluded that subjects who received 81 mg ASA daily could undergo dental extraction without bleeding risks.
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Nasser Nooh (2009) conducted a cohort in Dental extraction (n=189). Aspirin (Acetylsalicylic acid) vs. No aspirin was evaluated on Bleeding after dental extraction. Subjects receiving 81 mg aspirin daily could undergo dental extraction without bleeding risks, with similar bleeding outcomes across all groups at 48 hours and 5 days post-operatively.
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