Key result
Between 1999 and 2020, the age-adjusted mortality rate for hypertensive diseases in the USA increased from 15.8 to 29.1 per 100,000 individuals, with the highest rates in men and NH Blacks.
Why the study?
Hypertension is prevalent among one-third of US adults and significantly increases cardiovascular and non-cardiovascular mortality, but patterns and regional disparities required analysis.
Population
1,479,884 individuals who died of hypertensive diseases in the USA
Design
Retrospective database analysis using joinpoint regression
Authors
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Highlights regional hypertension mortality disparities; hypothesis-generating and should not yet change practice.
Observational (n=1,479,884)
Absolute Event Rate: 29.1% vs 15.8%
Hypertension mortality rates in the USA have significantly increased from 1999 to 2020, with disproportionately higher rates among men, NH Blacks, older adults, and those in Southern and urban areas.
Shaukat et al. (2025) conducted an observational in Hypertensive disease (n=1,479,884). Time period (1999-2020) vs. 1999 (baseline) was evaluated on Age-adjusted mortality rate (AAMR) per 100,000 individuals. Between 1999 and 2020, the age-adjusted mortality rate for hypertensive diseases in the USA increased from 15.8 to 29.1 per 100,000 individuals, with the highest rates in men and NH Blacks.
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