Key result
Sepsis-induced myocardial dysfunction presents as typical septic cardiomyopathy or sepsis-related takotsubo cardiomyopathy, necessitating careful evaluation of both ventricles.
Highlights the complexity of diagnosing and differentiating types of sepsis-induced myocardial dysfunction, including typical septic cardiomyopathy and sepsis-related takotsubo cardiomyopathy.
Sepsis-induced myocardial dysfunction is common. In addition to acute coronary syndrome, at least two types of left ventricular dysfunction can occur in septic patients: typical septic cardiomyopathy (SC) and sepsis-related takotsubo cardiomyopathy (ST). Although the definition of septic cardiomyopathy is based on left ventricular (LV) systolic dysfunction, both ventricles can be affected. In this context, it has been increasingly recognized that right ventricular (RV) systolic dysfunction is associated with long-term prognosis in septic patients. Unlike typical SC, ST patients usually displayed LV apical and circumferential mid-ventricular hypokinesia and basal hypercontractility. Timely and precise evaluation of heart dysfunction in sepsis patients is not easy but obviously mandatory. Further studies are still warranted regarding the mechanism, evaluation, and management of septic cardiomyopathy.
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Zhang et al. (2022) conducted a review in Sepsis-induced myocardial dysfunction. Sepsis-induced myocardial dysfunction presents as typical septic cardiomyopathy or sepsis-related takotsubo cardiomyopathy, necessitating careful evaluation of both ventricles.
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