Key result
Total artificial heart implantation was technically feasible following subtotal heart excision for an aggressive undifferentiated high-grade sarcoma, though the patient died on postoperative day 16.
Case Report (n=1)
No
Total artificial heart implantation can be considered as a viable surgical option for patients with aggressive cardiac tumors where partial resection is not feasible.
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May offer salvage in select unresectable cardiac sarcomas; leaves open need for prospective validation.
BACKGROUND Total artificial heart (TAH) implantation in patients with aggressive tumor infiltration of the heart can be challenging. CASE REPORT We report on a patient with a rare primary undifferentiated high-grade spindle cell sarcoma of the mitral valve and in the left atrium, first diagnosed in 2014. The referring center did a first resection in 2014. In the course of 17 months, computer tomography (CT) scan again showed massive invasion of the mitral valve and left atrium. Partial resection and mitral valve replacement was not an option. We did a subtotal heart excision with total artificial heart implantation. In this report we discuss complications, risk factors, and perioperative management of this patient. CONCLUSIONS Patients with aggressive tumors of the heart can be considered for TAH implantation.
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Kremer et al. (2016) conducted a case report in Undifferentiated high-grade spindle cell sarcoma of the heart (n=1). Total artificial heart (TAH) implantation was evaluated on Clinical outcome. Total artificial heart implantation was technically feasible following subtotal heart excision for an aggressive undifferentiated high-grade sarcoma, though the patient died on postoperative day 16.
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