Key result
Nonpulsatile biventricular bypass in animals led to the gradual development of regular arterial pressure fluctuations, reaching 12.4 mm Hg by 90 days, suggesting adaptive idioperipheral pulsation.
Population
5 long-term animals (calves) with fibrillated ventricles
Design
Preclinical
Follow-up
up to 99 days
Authors
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Adaptive pulsations may emerge during nonpulsatile bypass in animals; leaves open relevance to human mechanical support.
Animals on nonpulsatile biventricular bypass may develop active peripheral arterial pulsations ('idioperipheral pulsation') as an adaptation to maintain adequate peripheral circulation.
Tsutsui et al. (1986) studied Nonpulsatile biventricular bypass (n=5). Nonpulsatile biventricular bypass was evaluated on Arterial pressure fluctuations. Nonpulsatile biventricular bypass in animals led to the gradual development of regular arterial pressure fluctuations, reaching 12.4 mm Hg by 90 days, suggesting adaptive idioperipheral pulsation.
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