Key result
Altered heparin response during cardiopulmonary bypass cannot be predicted by preoperative antithrombin alone, whereas postoperative antithrombin levels are independently associated with major adverse cardiac events.
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This editorial highlights the limitations of using activated clotting time (ACT) to monitor heparin during cardiopulmonary bypass and emphasizes the complex role of antithrombin in heparin responsiveness and postoperative outcomes.
Levy et al. (2010) conducted an editorial in Cardiac surgery with cardiopulmonary bypass. Antithrombin and Heparin was evaluated. Altered heparin response during cardiopulmonary bypass cannot be predicted by preoperative antithrombin alone, whereas postoperative antithrombin levels are independently associated with major adverse cardiac events.
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