A [La(OTf)3] complex with a new pyBOX ligand bearing a bulky 1‐naphthylmethyl substituent at the 4′‐position of the oxazoline ring catalyzes the conjugate addition of nitroalkanes to a broad range of (E)‐2‐azachalcones, providing the expected nitro‐Michael products with good yields and enantiomeric excesses up to 87 %. The optical purity of the products can be increased by a single crystallization. A plausible stereochemical model to account for the observed stereochemistry has been proposed.
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Blay et al. (2013) studied this question.
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