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January 1, 2008Journal of EpidemiologyOpen Access

Epidemiologic Features of Kawasaki Disease in Japan: Results from the Nationwide Survey in 2005-2006

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Key result

The incidence of Kawasaki disease in Japan is continuously increasing, reaching an average annual incidence rate of 184.6 per 100,000 children aged 0-4 years in 2005-2006.

Population

20,475 patients with Kawasaki disease in Japan reported from 1,543 pediatric departments and hospitals.

Design

Cross-sectional

Follow-up

1 month (for cardiac sequelae)

Authors

YNYosikazu NakamuraGeneral / Preventive / LipidsMYMayumi YashiroJichi Medical UniversityRURitei UeharaNational Institute of Public Health

Discussion

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Implication

Rising Kawasaki disease incidence warrants surveillance in Japan; leaves open etiologic research and sequelae prevention needs.

Study Design

Type

Observational (n=20,475)

Multicenter

Yes

Structured PICO

P
Population
20,475 children diagnosed with Kawasaki disease in Japan between 2005 and 2006, analyzed to determine the national incidence rate and epidemiological trends.
O
Outcome
Annual incidence rate and number of patients with Kawasaki disease

The incidence of Kawasaki disease in Japan continues to rise, reaching 184.6 per 100,000 children aged 0-4 years in 2005-2006, with cardiac sequelae remaining a persistent clinical challenge.

Limitations

  • The survey response rate of 70.7% means the actual number of patients is likely higher than observed.
  • Potential double registration of patients who were referred to other hospitals due to disease severity.
  • Lack of specific diagnostic biomarkers means all patients were diagnosed clinically based on guidelines.
  • Lack of specific diagnostic findings, relying on pediatrician diagnosis based on guidelines
  • Potential for double registration of patients referred to multiple hospitals due to disease severity

Cite This Study

Nakamura et al. (2008) conducted an observational in Kawasaki disease (n=20,475). Calendar year (2005-2006) was evaluated on Average annual incidence rate per 100,000 children aged 0-4 years. The incidence of Kawasaki disease in Japan is continuously increasing, reaching an average annual incidence rate of 184.6 per 100,000 children aged 0-4 years in 2005-2006.

synapsesocial.com/papers/6a93c3f8a17c815a747bfe0chttps://doi.org/10.2188/jea.je2008001
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Increasing incidence of Kawasaki disease in Japan: Nationwide survey2008 · 100 citations
  2. 2Incidence Survey of Kawasaki Disease in 1997 and 1998 in Japan2001 · 170 citations
  3. 3Update of the Epidemiology of Kawasaki Disease in Japan1996 · 56 citations
  4. 4Older Age Is a Risk Factor for the Development of Cardiovascular Sequelae in Kawasaki Disease2004 · 63 citations