Key result
Coronary artery disease severity was associated with significantly elevated RBC aggregation compared to healthy controls (p<0.001), with the highest levels in acute myocardial infarction.
Population
69 participants including 16 healthy controls, 16 stable angina patients, 18 unstable angina patients, and…
Design
Cross-sectional
Authors
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May support RBC aggregation as CAD severity marker; leaves open causal role and need for prospective validation.
Observational (n=69)
p-value: p=<0.001
Hemorheological abnormalities, such as increased RBC aggregation and blood viscosity, correlate with the clinical severity of coronary artery disease.
Lee et al. (2008) conducted an observational in Stable angina and acute coronary syndromes (n=69). Coronary artery disease (SA, UA, AMI) vs. Healthy controls was evaluated on RBC aggregation (p=<0.001). Coronary artery disease severity was associated with significantly elevated RBC aggregation compared to healthy controls (p<0.001), with the highest levels in acute myocardial infarction.
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