Key result
Heparin reactions in patients with vascular disease are uncommon, decreasing in incidence due to greater drug purity, and are generally assumed to represent an immunologic hypersensitivity response.
Why the study?
What are the adverse reactions to heparin in patients with vascular disease?
Population
Patients with vascular disease
Design
Review
Authors
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Clinicians should monitor for rare heparin hypersensitivity in vascular patients; leaves open mechanistic confirmation and incidence trends.
What are the adverse reactions to heparin in patients with vascular disease?
Heparin reactions, though uncommon and decreasing in incidence due to improved drug purity, can range from alopecia to severe anaphylaxis and are generally considered hypersensitivity responses.
Jeremiah G. Turcotte (1965) conducted a review in Vascular Disease. Heparin was evaluated. Heparin reactions in patients with vascular disease are uncommon, decreasing in incidence due to greater drug purity, and are generally assumed to represent an immunologic hypersensitivity response.
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