Key result
A protein-rich meal evoked a more sustained increase in postprandial renal blood flow index than a carbohydrate-rich meal, with significantly higher levels at 180 and 240 minutes (P<0.05).
Why the study?
Does protein or carbohydrate ingestion alter renal blood flow and cardiac output in healthy adults?
Population
5 healthy adults
Comparison
Ingestion of equivolume meals: 1) 150 g protein… vs Water (500 ml) and fasting baseline
Design
RCT, Studied randomly on three separate days
Follow-up
240 minutes postprandially
Authors
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Protein-rich meals may sustain renal perfusion longer postprandially; extends evidence on macronutrient effects for trials in CKD.
RCT (n=5)
Randomized
Does protein or carbohydrate ingestion alter renal blood flow and cardiac output in healthy adults?
p-value: p=<0.05
A protein-rich meal evokes a more sustained increase in postprandial renal blood flow index compared to a carbohydrate-rich meal, though the percentage of cardiac output perfusing the kidney declines similarly with both.
Avasthi et al. (1987) conducted an RCT in Healthy (n=5). Protein-rich meal vs. Carbohydrate-rich meal and water was evaluated on Renal blood flow index (RI) and percentage of cardiac index distributed to a single kidney (%CI) (p=<0.05). A protein-rich meal evoked a more sustained increase in postprandial renal blood flow index than a carbohydrate-rich meal, with significantly higher levels at 180 and 240 minutes (P<0.05).
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