Key result
High-carbohydrate meals increased cardiac output by 32% at 30 minutes compared to 22% for high-fat meals (P=0.03), while eliciting significantly different regional vascular responses.
Why the study?
Does a high-fat meal compared to a high-carbohydrate meal elicit different cardiovascular and metabolic responses in healthy young subjects?
Population
Healthy young subjects, mean age 23 years (range 19-39)
Comparison
High-fat (F) meal vs High-carbohydrate (C) meal
Design
Other
Follow-up
60 minutes postprandially
Authors
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Acute postprandial hemodynamic differences in healthy subjects should not change practice; leaves open relevance to long-term risk or patients.
Does a high-fat meal compared to a high-carbohydrate meal elicit different cardiovascular and metabolic responses in healthy young subjects?
Absolute Event Rate: 32% vs 22%
p-value: p=0.03
High-carbohydrate and high-fat meals elicit different regional vascular and metabolic responses in healthy young subjects despite similar increases in overall cardiac output.
Sidery et al. (1991) studied Healthy. High-carbohydrate meal vs. High-fat meal was evaluated on Cardiac output increase at 30 minutes (p=0.03). High-carbohydrate meals increased cardiac output by 32% at 30 minutes compared to 22% for high-fat meals (P=0.03), while eliciting significantly different regional vascular responses.
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