Key result
A case report describes the youngest child presenting with the rare triad of severe hypertriglyceridemia, acute pancreatitis, and diabetic ketoacidosis in new-onset type-I diabetes mellitus.
Case Report (n=1)
This case highlights the rare occurrence of severe hypertriglyceridemia-induced acute pancreatitis in a pediatric patient presenting with diabetic ketoacidosis.
May alert clinicians to pancreatitis risk in pediatric DKA with hypertriglyceridemia; leaves open incidence and management questions.
Around 25% of newly diagnosed diabetic children present with diabetic ketoacidosis at the onset. Severe hypertriglyceridemia (triglyceride [TG] >1000 mg/dL) is another rare complication of ketoacidosis which increases the risk of acute pancreatitis. Pancreatitis attributable to hypertriglyceridemia was seen in 4% of diabetic ketoacidosis episodes in adults. However, the triad of acute pancreatitis caused by hypertriglyceridemia, along with diabetic ketoacidosis and its treatment, has not been extensively discussed in the pediatric literature. Only eight cases have been reported previously. We report the youngest child with the triad of severe hypertriglyceridemia, acute pancreatitis, and diabetic ketoacidosis.
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Sharma et al. (2017) conducted a case report in New-onset Type-I Diabetes Mellitus with Diabetic Ketoacidosis, Severe Hypertriglyceridemia, and Acute Pancreatitis (n=1). Severe hypertriglyceridemia was evaluated. A case report describes the youngest child presenting with the rare triad of severe hypertriglyceridemia, acute pancreatitis, and diabetic ketoacidosis in new-onset type-I diabetes mellitus.
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