Key result
Quantitative pupillometry provides objective and reliable parameters for assessing changes in pupillary light reflexes, offering prognostic value for outcomes after cardiac arrest and monitoring in the neuroICU.
Why the study?
Quantitative pupillometers provide objective parameters for pupillary light reflex assessment, warranting a review of their physiology, parameters, and clinical applications in neuroICU care.
Quantitative pupillometry serves as an objective and important monitoring tool for neurological diseases and post-cardiac arrest prognostication in the neuroICU.
Supports quantitative pupillometry in neuroICU protocols; leaves open need for prospective validation of prognostic value post-arrest.
The pupillary light reflex (PLR) is a component of bedside neurological examinations in neurological intensive care units (neuroICUs). A quantitative pupillometer provides a non-invasive and objective pupil reactivity parameter clinically significant for changes in PLR in neuroICUs. This article reviews the physiology and importance of the PLR and the parameters of quantitative pupillometers. Moreover, this review discusses the clinical applications of quantitative pupillometers for post-cardiac arrest prognostication and monitoring of elevated intracranial pressure and neurological worsening in stroke, seizures, and other neurological diseases in the neuroICU. Quantitative pupillometry is a routine part of neurological examinations and an important monitoring tool for neurological diseases in neuroICUs.
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Tae Jung Kim (2022) conducted a review in Neurocritical illness. Quantitative pupillometry vs. Manual pupil examination was evaluated. Quantitative pupillometry provides objective and reliable parameters for assessing changes in pupillary light reflexes, offering prognostic value for outcomes after cardiac arrest and monitoring in the neuroICU.
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