Key result
Angiotensin-converting-enzyme inhibitors and calcium-channel blockers largely replaced diuretics in the late 1980s and early 1990s as the preferred hypertension therapy for older patients.
A review discussing the historical shift in antihypertensive prescribing practices away from diuretics toward ACE inhibitors and CCBs.
May warrant reappraisal of diuretic preference in older patients; leaves open whether the documented shift improved outcomes.
By the end of the 1980s and early 1990s a major shift occurred in the choice of pharmacologic therapy for hypertension. Many physicians stopped prescribing diuretics for older patients with hypertension in favour of angiotensin-converting- enzyme (ACE) inhibitors and calcium-channel blockers (CCBs
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Frans H. H. Leenen (2004) studied this question. Angiotensin-converting-enzyme inhibitors and calcium-channel blockers largely replaced diuretics in the late 1980s and early 1990s as the preferred hypertension therapy for older patients.
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