Key result
In 32 pediatric infective endocarditis episodes, congenital heart disease was the main risk factor (87.5%), and a high proportion (27.8%) were caused by non-HACEK Gram-negative bacteria.
Why the study?
Recent changes in pediatric care could have influenced the microbiology and presentation of infective endocarditis, a rare disease linked with significant morbimortality.
Population
32 IE episodes in pediatric patients < 16 years old
Design
Descriptive observational retrospective single-center study
Authors
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Supports heightened vigilance for non-HACEK Gram-negatives in pediatric IE with CHD; leaves open need for adjusted empiric regimens pending larger studies.
Observational (n=32)
No
The proportion of pediatric infective endocarditis cases attributed to non-HACEK Gram-negative bacteria is higher than previously reported, suggesting an evolving epidemiology that may require empirical MDRB coverage in colonized patients.
Marín‐Cruz et al. (2024) conducted an observational in Infective endocarditis (n=32). Infective endocarditis was evaluated on Microbiological etiology and clinical complications. In 32 pediatric infective endocarditis episodes, congenital heart disease was the main risk factor (87.5%), and a high proportion (27.8%) were caused by non-HACEK Gram-negative bacteria.
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