Key result
Age and diabetes mellitus were strongly and independently associated with an increase in common carotid artery intima-media thickness in patients with acute ischemic stroke (P<0.001).
Observational (n=381)
p-value: p=<0.001
In patients with acute ischemic stroke, increased carotid intima-media thickness is independently associated with advancing age and the presence of diabetes mellitus.
Supports risk stratification by age and diabetes in acute ischemic stroke; leaves open causal progression and intervention effects.
Background: Common carotid artery intima-media thickness (IMT) is an accepted sonographic marker of early atherosclerosis, and increased IMT represents a risk of ischemic stroke. The purpose of this study was to evaluate the correlation between common carotid artery IMT and stroke risk factors in patients with ischemic stroke. Methods: Subjects were 381 patients with acute ischemic stroke. High resolution B-mode ultrasonography was performed to measure IMT at common carotid artery. Multivariate regression analysis was performed to determine the independent factors related to common carotid artery IMT. Results: The variables that strongly predicted an increase in the common carotid artery IMT were age (P<0.001) and diabetes mellitus (P<0.001). Conclusion: Increased common carotid artery IMT is independently associated with age and diabetes mellitus in patients with ischemic stroke. (Korean J Stroke 2011;13:129-133)
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Kim et al. (2011) conducted an observational in Acute ischemic stroke (n=381). Age and diabetes mellitus was evaluated on Increase in common carotid artery intima-media thickness (IMT) (p=<0.001). Age and diabetes mellitus were strongly and independently associated with an increase in common carotid artery intima-media thickness in patients with acute ischemic stroke (P<0.001).
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