Key result
Mean common carotid intima-media thickness was significantly higher in patients with established coronary artery disease compared to controls without significant clinical coronary artery disease (0.86 mm vs 0.58 mm, p<0.001).
Why the study?
Is common carotid intima-media thickness associated with the presence of coronary artery disease?
Case-Control (n=180)
No
Is common carotid intima-media thickness associated with the presence of coronary artery disease?
Absolute Event Rate: 0.86% vs 0.58%
p-value: p=<0.001
Common carotid intima-media thickness is significantly elevated in patients with coronary artery disease, and a cut-off of 0.8 mm provides high specificity for identifying significant CAD.
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Hypothesis-generating for B-mode ultrasonography in subclinical atherosclerosis detection; should not yet change CAD prevention practice.
Srinivasa Rao Malladi (2015) conducted a case-control in Coronary Artery Disease (n=180). Common carotid intima-media thickness (IMT) vs. Controls (normal coronary arteries) was evaluated on Mean common carotid intima-media thickness (IMT) (p=<0.001). Mean common carotid intima-media thickness was significantly higher in patients with established coronary artery disease compared to controls without significant clinical coronary artery disease (0.86 mm vs 0.58 mm, p<0.001).
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