Key result
Metabolic syndrome defined by the NCEP ATP III criteria was associated with a significantly higher risk of new-onset cardiovascular disease in rural elderly females (HR 1.45), but not in males.
Why the study?
It was unknown whether metabolic syndrome and its components could predict cardiovascular disease in a rural elderly Chinese population.
Does metabolic syndrome predict newly onset cardiovascular disease in an elderly rural Chinese population?
Population
2486 elderly individuals from rural China
Comparison
Metabolic syndrome and its components vs absence
Design
Longitudinal cohort study
Authors
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MetS predicted incident CVD in rural elderly Chinese women but not men; leaves open sex-specific screening utility pending prospective validation.
Cohort (n=2,486)
Does metabolic syndrome predict newly onset cardiovascular disease in an elderly rural Chinese population?
Hazard Ratio: 1.45 (95% CI 1–2.1)
Metabolic syndrome is a significant predictor of incident cardiovascular disease in elderly rural Chinese females, but not males, highlighting a gender discrepancy in risk.
Yu et al. (2021) conducted a cohort in Cardiovascular disease (n=2,486). Metabolic syndrome (NCEP ATP III criteria) vs. Without metabolic syndrome was evaluated on New-onset cardiovascular disease (CVD) in females (HR 1.45, 95% CI 1.00, 2.10). Metabolic syndrome defined by the NCEP ATP III criteria was associated with a significantly higher risk of new-onset cardiovascular disease in rural elderly females (HR 1.45), but not in males.