Key result
Central obesity, defined by high waist circumference, increased the risk of incident hypertension by 33% (HR 1.33) compared to normal waist circumference, demonstrating a stronger predictive value than body mass index.
Why the study?
Obesity is linked to an increased risk of hypertension, but the optimal adiposity indicators to predict hypertension remain controversial.
Do central adiposity indicators predict the risk of hypertension better than body mass index in an adult population?
Cohort (n=5,613)
Yes
Do central adiposity indicators predict the risk of hypertension better than body mass index in an adult population?
Hazard Ratio: 1.33 (95% CI 1.12–1.57)
p-value: p=<0.01
Central adiposity indicators such as waist circumference and waist-to-height ratio are stronger predictors of hypertension risk than BMI, highlighting the importance of waist circumference management.
May aid hypertension risk stratification via adiposity metrics in Southwest China; hypothesis-generating and requires prospective validation.
Objectives:Studies have linked obesity to an increased risk of hypertension, but the optimal adiposity indicators to predict hypertension remains controversial. We comprehensively explored the correlation between body mass index, waist circumference (WC), waist-to-height ratio (WHtR), long-term weight and WC change, and hypertension in an adult population in Southwest China. Methods:We studied 9,280 participants from 48 townships of 12 districts with a follow-up of 10 years in the Guizhou Population Health Cohort Study. We used Pearson’s correlation coefficients combined with Dunn and Clark’s z test and Zou’s confidence interval test, receiver operating characteristic (ROC) analyses, and multivariate Cox proportional hazards regressions adjusting for demographic characteristics, lifestyle habits, disease history, and lipid information of participants. Results:Baseline central adiposity indicators (WC and WHtR) had closer associations with hypertension than BMI, and long-term WC change was more predictive of hypertension compared with weight change in the studied population. Conclusion:Central adiposity indicators maintain a stronger association with the risk of hypertension, hinting at the importance of WC management in the precaution of hypertension.
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Liu et al. (2022) conducted a cohort in Hypertension (n=5,613). Central obesity (waist circumference ≥85 cm for women, ≥90 cm for men) vs. Normal waist circumference (<85 cm for women, <90 cm for men) was evaluated on Incident hypertension (HR 1.33, 95% CI 1.12-1.57, p=<0.01). Central obesity, defined by high waist circumference, increased the risk of incident hypertension by 33% (HR 1.33) compared to normal waist circumference, demonstrating a stronger predictive value than body mass index.