Why the study?
The study was conducted to determine the correlation of zero coronary artery calcium score with non-significant coronary artery stenosis using computed tomography coronary angiography.
Does a zero coronary artery calcium score exclude significant coronary artery stenosis in high-risk asymptomatic patients with suspected CAD?
Population
62 patients with suspected CAD
Comparison
CACS vs CTCA-assessed coronary artery stenosis
Design
Cross-sectional study
Key result
A zero coronary artery calcium score strongly correlated with the absence of significant coronary artery stenosis (rs=0.872, p<0.001), effectively excluding significant disease in high-risk asymptomatic patients.
Authors
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May support deferring CTCA in zero-CACS patients; leaves open larger prospective studies before practice change.
Cross-Sectional (n=62)
No
Does a zero coronary artery calcium score exclude significant coronary artery stenosis in high-risk asymptomatic patients with suspected CAD?
Effect estimate: rs = 0.872
p-value: p=<0.001
A zero coronary calcium score effectively excludes significant coronary artery stenosis in high-risk asymptomatic patients, supporting its use as a screening tool prior to coronary angiography.
Afzal et al. (2022) conducted a cross-sectional in Suspected coronary artery disease (n=62). Coronary artery calcium score (CACS) was evaluated on Correlation between coronary calcium score and maximum coronary luminal stenosis (rs = 0.872, p=<0.001). A zero coronary artery calcium score strongly correlated with the absence of significant coronary artery stenosis (rs=0.872, p<0.001), effectively excluding significant disease in high-risk asymptomatic patients.
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