Key result
A combination of nerve conduction studies, quantitative sensory testing, and autonomic function testing is recommended for assessing peripheral nerve function in long-term polyneuropathy trials.
Why the study?
What are the most sensitive and reproducible testing modalities to detect changes in peripheral nerve function during long-term clinical trials for polyneuropathy?
Population
Patients with diabetic and other forms of polyneuropathy participating in clinical trials
Design
Review
Authors
Loading...
May guide endpoint selection in polyneuropathy trials; leaves open optimal combination pending prospective validation.
What are the most sensitive and reproducible testing modalities to detect changes in peripheral nerve function during long-term clinical trials for polyneuropathy?
A combination of nerve conduction, quantitative sensory, and autonomic function testing is recommended to reliably detect changes in peripheral nerve function in polyneuropathy clinical trials.
Richard K. Olney (1998) conducted a review in Polyneuropathy. Nerve conduction studies, quantitative sensory testing, and autonomic function testing was evaluated. A combination of nerve conduction studies, quantitative sensory testing, and autonomic function testing is recommended for assessing peripheral nerve function in long-term polyneuropathy trials.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: