Key result
A simplified microplate tissue culture procedure for viral neutralization antibody surveys was as sensitive as and far more economical than standard tube cultures.
A microplate tissue culture procedure provides a sensitive and economical alternative to standard tube cultures for viral neutralization antibody surveys.
May offer labs a lower-cost option for neutralization assays; leaves open validation across viruses before wider use.
A simplified, microplate tissue culture procedure is described which facilitates neutralization antibody surveys on large numbers of sera. A comparison of the micromethod with that employing standard tube cultures indicates it to be as sensitive and far more economical.
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Helmke et al. (1970) studied this question. A simplified microplate tissue culture procedure for viral neutralization antibody surveys was as sensitive as and far more economical than standard tube cultures.
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