Key result
Needle biopsies of the liver in 30 patients with heart failure demonstrated that clinical and biochemical studies could not predict hepatic anatomy with certainty.
Why the study?
Does needle biopsy of the liver provide additional diagnostic information beyond clinical and biochemical evaluation in patients with heart failure?
Observational (n=30)
Does needle biopsy of the liver provide additional diagnostic information beyond clinical and biochemical evaluation in patients with heart failure?
Hepatic biopsy is a useful adjunct in heart failure patients, as clinical and biochemical evaluations are insufficient to predict liver histology with certainty.
Needle biopsies of the liver were performed on 30 patients with heart failure and correlated with clinical features and biochemical liver function studies. Hepatic biopsy served as a useful adjunct to other methods in deciding the status of the liver in this group. Type of heart disease, degree of heart failure and length of heart failure could not be correlated with the observed histology. Neither history, physical examination, nor biochemical functional studies provided sufficient information to predict anatomy with certainty. A histologic diagnosis improved both therapeutic and prognostic perspective.
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White et al. (1951) conducted an observational in Congestive Heart Failure (n=30). Needle biopsies of the liver was evaluated on Correlation of hepatic histology with clinical features and biochemical liver function studies. Needle biopsies of the liver in 30 patients with heart failure demonstrated that clinical and biochemical studies could not predict hepatic anatomy with certainty.
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