July 1, 1985Circulation
Results of triple valve replacement in 91 patients: perioperative mortality and long-term follow-up.
Key result
Simultaneous triple valve replacement resulted in 44% perioperative mortality for NYHA class IV patients compared to 8% for milder symptoms (p<0.0001), with an overall 10-year survival of 40%.
Population
91 patients who underwent simultaneous triple valve replacement between 1961 and 1984
Design
Cohort
Follow-up
median 7.5 years (range, 6 weeks to 20 years)
Authors
Discussion
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Implication
High perioperative mortality in NYHA IV warrants cautious selection for triple valve replacement; this Level 3 cohort data leaves open optimal criteria for prospective trials.
Study Design
Type
Cohort (n=91)
Multicenter
No
Structured PICO
P
Population
91 patients who underwent simultaneous triple valve replacement, followed for a median of 7.5 years.
E
Exposure
Simultaneous triple valve replacement
O
Outcome
Perioperative (30 day) mortality and long-term cumulative survivalhard clinical
Main Result
Absolute Event Rate: 44% vs 8%
p-value: p=<0.0001
Simultaneous triple valve replacement offers acceptable long-term survival and excellent symptomatic improvement for 30-day survivors, though it is associated with high late morbidity.
Cite This Study
Gersh et al. (1985) conducted a cohort in Valvular heart disease requiring triple valve replacement (n=91). Simultaneous triple valve replacement vs. Milder symptoms (NYHA class I-III) was evaluated on Perioperative (30 day) mortality in NYHA class IV vs milder symptoms (p=<0.0001). Simultaneous triple valve replacement resulted in 44% perioperative mortality for NYHA class IV patients compared to 8% for milder symptoms (p<0.0001), with an overall 10-year survival of 40%.