Key result
Zinc depressed the contractile force of rat atria and caused a statistically significant fall in atrial calcium content, likely due to interference in cellular calcium handling.
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Alerts clinicians to possible zinc effects on atrial function; leaves open translation from rat models to human disease.
Ciofalo et al. (1965) studied this question. Zinc was evaluated on Contractile force, membrane potentials, and cation content. Zinc depressed the contractile force of rat atria and caused a statistically significant fall in atrial calcium content, likely due to interference in cellular calcium handling.
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