Key result
Primary percutaneous coronary intervention was associated with a 20.0% incidence of complete AV block compared to 11.11% in patients receiving standard thrombolytic therapy.
Why the study?
The study was conducted to develop a risk stratification model incorporating identified predictors to estimate the individual risk of complete AV block in patients undergoing primary PCI for acute inferior STEMI.
Cross-Sectional (n=139)
No
The study developed a risk stratification model to predict complete AV block in patients with acute inferior STEMI undergoing primary PCI, highlighting the importance of culprit lesion location.
Answers are grounded in this paper and cite their sources.
Primary PCI may confer higher complete AV block risk than thrombolysis in inferior STEMI; leaves open need for prospective validation of risk models.
Background: Acute inferior ST-elevation myocardial infarction (STEMI) is medical emergency entailing immediate intervention to restore blood flow and mitigate myocardial damage. Primary percutaneous coronary intervention (PCI) has replaced thrombolytic therapy as preferred treatment strategy for having superior outcomes. Objectives: To develop a risk stratification model incorporating the identified predictors to estimate the individual risk of complete AV block in patients undergoing primary PCI for acute inferior STEMI. Methods: This study enrolled 139 patients diagnosed with acute inferior STEMI who underwent primary PCI at the hospital. They were divided into two groups, i.e. pre-operative and post-operative carrying 54 and 85 patients, respectively. On admission, demographic, clinical data and peak values of cardiac biomarkers were obtained and the complications associated with PCI were elaborated. Results: Mean age of patients was 59.81+8.19 years, and comprised significantly more male (97) than female (42) patients (p<0.05). Proportion of patients with a history of complete AV block was 10.79%. Comorbidities included diabetes mellitus (33.09%), hypertension (49.64%), and dyslipidemia (64.74%).Coronary angiography findings for predicting AV block in patients with STEMI were categorized by location of culprit lesion in coronary vessels.
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Khan et al. (2023) conducted a cross-sectional in Acute inferior STEMI (n=139). Primary percutaneous coronary intervention (PCI) vs. Standard thrombolytic therapy (without PCI) was evaluated on Development of complete AV block (p=0.0011). Primary percutaneous coronary intervention was associated with a 20.0% incidence of complete AV block compared to 11.11% in patients receiving standard thrombolytic therapy.
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