Key result
New conduction blocks in STEMI carry ~39% in-hospital MACE rate after primary PCI.
Why the study?
Conduction disturbances are common complications of acute STEMI and their clinical outcomes after primary PCI during hospital stay need assessment.
Observational (n=100)
STEMI patients presenting with new-onset conduction abnormalities undergoing primary PCI experience a high rate (39%) of in-hospital major adverse cardiac events.
Supports close surveillance for STEMI patients with conduction disorders; leaves open whether these abnormalities warrant targeted interventions beyond revascularization.
Background Conduction disturbances, including bradycardia, atrioventricular blocks, and bundle branch blocks, are common complications of acute myocardial infarction and reflect ischemic injury to the conduction system. Timely reperfusion with primary percutaneous coronary intervention has improved outcomes by restoring coronary blood flow and reducing complications and mortality. Aim Purpose of the study was to assess clinical outcomes of patients who underwent primary percutaneous coronary intervention for acute ST elevation myocardial infarction (STEMI) associated with conduction abnormalities during hospital stay. Patients and methods This study was conducted on 100 patients with Acute STEMI associated with new-onset conduction abnormalities. Full history taking and clinical examination, risk factors assessment, laboratory assessment (ECG), echocardiographic, and coronary angiographic evaluation were carried out during hospital stay. Major adverse cardiac events were recorded during the in-hospital period (average 2 days). Results Most patients were males (65%), with a mean age 58.56 years. Smoking was the leading risk factor (78%) with 86% were classified as Killip I. Average door-to-balloon time (1.5 h), multi-vessel disease observed in (43%), with the most common culprit vessel being the right coronary artery in 63%. Tirofiban used in 16% and 95% had final thrombolysis in myocardial infarction flow III. A major adverse cardiac events occurred in 39%: mortality (2%), heart failure (12%), reinfarction (5%), bleeding (7%), and contrast-induced nephropathy (6%), with no strokes reported. Conclusion High-degree atrioventricular block in STEMI is associated with adverse in-hospital outcomes. Early recognition, rapid revascularization improves conduction recovery and reduce morbidity, and mortality.
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Shehata et al. (2026) conducted an observational in Acute ST elevation myocardial infarction (STEMI) with new-onset conduction abnormalities (n=100). Primary percutaneous coronary intervention in the setting of new-onset conduction abnormalities was evaluated on Major adverse cardiac events during the in-hospital period. Among 100 patients with acute STEMI and new-onset conduction abnormalities undergoing primary PCI, major adverse cardiac events occurred in 39% during the average 2-day in-hospital stay.
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