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August 25, 2020CureusOpen Access

Impact of Primary Percutaneous Coronary Intervention on Complete Atrioventricular Block With Acute Inferior ST-Elevation Myocardial Infarction

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Key result

In patients with acute inferior STEMI undergoing primary PCI, the presence of complete atrioventricular block did not significantly increase in-hospital mortality, and the block resolved in 66.6% of affected patients.

Why the study?

Complete atrioventricular block is associated with poor clinical outcomes in STEMI, motivating an evaluation of the frequency and outcomes of primary percutaneous coronary intervention in patients with CAVB complicating acute inferior STEMI.

Does the presence of complete atrioventricular block (CAVB) affect in-hospital mortality in patients with acute inferior STEMI undergoing primary percutaneous coronary intervention (PPCI)?

Population

151 patients diagnosed with inferior STEMI receiving PPCI

Comparison

Patients with CAVB vs without CAVB

Design

Observational, prospective study

Follow-up

Two weeks

Authors

JMJahanzeb MalikCross-Cutting CardiologyTLTalha LaiqueInternational Labour OrganizationMFMuhammad Hasan Farooq

Discussion

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Implication

May not worsen in-hospital mortality after primary PCI; leaves open need for prospective data on long-term outcomes and management.

Study Design

Type

Observational (n=151)

Multicenter

No

Structured PICO

Does the presence of complete atrioventricular block (CAVB) affect in-hospital mortality in patients with acute inferior STEMI undergoing primary percutaneous coronary intervention (PPCI)?

P
Population
151 patients (mean age 57, 14.5% female) with acute inferior STEMI undergoing primary PCI, followed for two weeks to assess resolution of complete atrioventricular block and in-hospital mortality.
E
Exposure
Presence of complete atrioventricular block (CAVB)
C
Comparator
Absence of complete atrioventricular block (CAVB)
O
Outcome
In-hospital mortality at two weeks follow-uphard clinical

Main Result

Absolute Event Rate: 9.5% vs 2.3%

p-value: p=>0.05

Primary PCI is effective in reverting complete atrioventricular block in acute inferior STEMI, resulting in in-hospital mortality comparable to patients without heart block.

Limitations

  • Single-centre study
  • Small sample size
  • Extensive patient characteristics not included
  • Type of pacemakers not analyzed
  • Short follow-up time
  • Disease burden not assessed

Cite This Study

Malik et al. (2020) conducted an observational in Acute inferior ST-elevation myocardial infarction (n=151). Complete atrioventricular block (CAVB) vs. No CAVB was evaluated on In-hospital mortality (p=>0.05). In patients with acute inferior STEMI undergoing primary PCI, the presence of complete atrioventricular block did not significantly increase in-hospital mortality, and the block resolved in 66.6% of affected patients.

synapsesocial.com/papers/6a93e8363184263e278f99ebhttps://doi.org/10.7759/cureus.10013
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