Key result
Complete AV block in anterior STEMI predicts ~82% mortality and MACCE, unlike nonanterior infarcts.
Why the study?
Although complete atrioventricular block had higher mortality in the thrombolytic era, little was known about its clinical impact on STEMI patients undergoing primary PCI.
Does complete atrioventricular block increase the risk of all-cause death and MACCE in STEMI patients undergoing primary PCI?
Population
1295 STEMI patients undergoing primary PCI within 24 hours from onset
Comparison
Patients with CAVB vs without CAVB, stratified by anterior vs nonanterior STEMI
Design
Consecutive observational cohort study
Follow-up
Median 3.8 (1.7-6.6) years
Authors
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CAVB signals high mortality risk in anterior STEMI; leaves open whether targeted interventions improve outcomes.
Cohort (n=1,295)
Does complete atrioventricular block increase the risk of all-cause death and MACCE in STEMI patients undergoing primary PCI?
p-value: p=<0.05
Complete atrioventricular block remains a poor prognostic complication in anterior STEMI patients undergoing primary PCI, independently predicting all-cause mortality and MACCE.
Kawamura et al. (2020) conducted a cohort in ST-segment elevation myocardial infarction (STEMI) (n=1,295). Complete atrioventricular block (CAVB) vs. No CAVB was evaluated on All-cause death and major adverse cardiocerebrovascular events (MACCE) (p=<0.05). Complete atrioventricular block in anterior STEMI patients independently predicted all-cause mortality (82% vs 20%, p<0.05) and MACCE (82% vs 25%, p<0.05), but not in nonanterior STEMI.
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