Key result
Calf muscle venous thrombosis is a frequent site of deep venous thrombosis that can propagate proximally if untreated, with variable evidence regarding the benefit of anticoagulation therapy.
Calf muscle venous thrombosis is a frequent area for DVT that can propagate proximally, but treatment recommendations for anticoagulation remain variable.
Should not yet alter practice for calf muscle venous thrombosis; leaves open optimal anticoagulation strategy pending prospective trials.
Calf muscle veins have been demonstrated to be one of the most frequent areas that develop deep venous thrombosis (DVT), both as an isolated finding and in combination with proximal DVT. Calf muscle venous thrombosis (CMVT) has been shown to be more frequently associated with localized calf tenderness, and when left untreated, a proportion tend to propagate proximally and may lead to pulmonary embolism. Imaging with duplex venous scanning is fairly sensitive in the diagnosis of CMVT. Treatment recommendations for CMVT are variable with some studies showing clear clinical benefit of anticoagulation therapy and others showing no benefit.
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Henry et al. (2014) conducted a review in Calf muscle venous thrombosis. Calf muscle venous thrombosis is a frequent site of deep venous thrombosis that can propagate proximally if untreated, with variable evidence regarding the benefit of anticoagulation therapy.
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